Afvallen met GLP-1 (Ozempic, Wegovy, Mounjaro): zo bescherm je je spiermassa met eiwitten

Losing Weight with GLP-1 (Ozempic, Wegovy, Mounjaro): How to Protect Your Muscle Mass with Protein

June 2, 2026Fajah Lourens

If you use GLP-1 medication, you will lose weight effectively, but without the right approach, you will also lose muscle mass. The solution: eat at least 1.6 grams of protein per kilogram of body weight per day and strength train 2–3 times a week.

On this page, you’ll find everything: why muscle mass matters, how much protein you need, how to achieve that when you have little appetite, and which products can help.

Why you lose muscle mass with GLP-1 medication

GLP-1 medication strongly suppresses your hunger. This creates a significant caloric deficit, and your body responds by not only burning fat but also breaking down muscle tissue for energy. Research shows that 25-40% of the weight lost with GLP-1 use can consist of fat-free mass.

How much protein do you need with GLP-1?

The guideline: at least 1.6 grams of protein per kilogram of body weight per day.

  • 70 kg: at least 112 grams per day
  • 80 kg: at least 128 grams per day
  • 90 kg: at least 144 grams per day

Little hunger, yet enough protein

Small, protein-rich, and easily digestible choices are key: cottage cheese, eggs, chicken breast, the Killerbody Meal Shake (approx. 28g protein per serving), Protein Water for in between meals.

Strength training: the second pillar

Your body needs a reason to retain those muscles. 2-3 targeted sessions per week are enough. Think squats, lunges, push-ups, rows with resistance bands.

Is a meal replacement useful with GLP-1?

Yes, provided you choose one that is complete: at least 25-30g of protein per serving, a full amino acid profile, vitamins, and minerals. The Killerbody Meal Shake has it all.

After stopping: how to prevent the yo-yo effect

If you have maintained your muscle mass during treatment, you will start with a higher resting metabolism after stopping. That makes all the difference in the long run.

The three steps summarized

  1. Eat enough protein - at least 1.6g per kg per day
  2. Strength train - 2-3 times a week
  3. Choose compact, protein-rich options - a Meal Shake helps if large meals are not feasible

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