Gewicht vasthouden na stoppen met GLP-1: zo voorkom je het jojo-effect

Maintaining weight after stopping GLP-1: how to prevent the yo-yo effect

June 2, 2026Fajah Lourens

Stopping GLP-1 medication like Ozempic or Mounjaro? Weight gain is a real possibility, but not inevitable. Research shows that people who preserved their muscle mass during treatment gained significantly less weight after stopping. Your muscles are your protection.

Why do you gain weight after stopping GLP-1?

GLP-1 medication artificially suppresses your hunger. When you stop, that hunger returns, often strongly. This is biology, not a lack of willpower. But two factors determine your starting position after stopping: how much muscle mass you've preserved (more muscle mass = higher resting metabolism) and whether you've built healthy eating habits.

Step 1: Start well-prepared

If you know you'll be stopping soon, make sure that in the final weeks of treatment you eat at least 1.2g of protein per kg of body weight daily, strength train 2-3 times a week, and establish an eating pattern that is sustainable without medication.

Step 2: Gradually build up appetite

Most doctors advise gradually tapering off GLP-1 medication. If your appetite returns: continue to prioritize protein-rich meals, avoid sugary snacks as comfort food, and use the Killerbody Meal Shake as a convenient protein-rich meal option if hunger feels overwhelming.

Step 3: Keep protein intake consistently high

Protein has the highest satiety per calorie of all macronutrients. By continuing to eat 1.2-1.6g of protein per kg per day: you'll feel fuller for longer, maintain your muscle mass and metabolism, and reduce the chance of the yo-yo effect.

Step 4: Continue strength training

After stopping GLP-1, strength training is your best ally. It keeps your muscles active, your metabolism high, and helps convert excess energy into muscle building instead of fat storage.

Long-term: Nutrition as a foundation

Women who maintain their protein intake, continue strength training, and keep their meal patterns intact after stopping are most successful in maintaining their results. The Killerbody 30-day packages and coaching are designed as a bridge: from treatment to an independent eating pattern that works.

Read also: Back to the pillar: Losing weight with GLP-1 | How much protein do you need with GLP-1?

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